Background: The long term goals of the lab are to understand the molecules and developmental programs that regulate neuronal development and wiring. In a previous study, we investigated the biology of the novel interactions between two subfamilies of the immunoglobulin superfamily in Drosophila melanogaster (in collaboration with Christopher Garcia at Stanford and Engin Ozkan at the University of Chicago; Ozkan et al., 2013): the defective proboscis extension response proteins (Dprs), encompassing 21 members, and the 9-member Dpr-interacting proteins (DIPs). These proteins are expressed in unique subsets of neurons throughout the nervous system and are implicated in various developmental processes. Previously, we found that an interacting Dpr-DIP pair functions at various developmental stages including motor neuron development at the larval neuromuscular junction (NMJ) and wiring and cell survival in the pupal optic lobe (Carrillo et al., 2015).